Precision oncology: Detection and treatment of TRK fusion-positive lung cancers

December 06, 2023 00:21:28
Precision oncology: Detection and treatment of TRK fusion-positive lung cancers
COR2ED - Oncology Medical Conversation
Precision oncology: Detection and treatment of TRK fusion-positive lung cancers

Dec 06 2023 | 00:21:28

/

Show Notes

In this medical education podcast, NTRK CONNECT members Assoc. Prof. Caterina Marchiò (University of Turin, Italy) and Prof. Christian Rolfo (Center of Thoracic Oncology Tisch Cancer Institute Icahn School of Medicine at Mount Sinai, New York, USA) provide pathologist and medical oncologist perspectives about the detection and treatment of TRK fusion-positive lung cancers.

They discuss a number of techniques and strategies to identify this rare fusion in lung cancer patients, before going on to summarise the robust efficacy and safety data for both entrectinib and larotrectinib. Prof. Rolfo briefly covers second-generation therapies in clinical development and describes how liquid biopsy is emerging as a new technique not only to identify but also monitor patients. They conclude by stressing the importance of the collaboration and communication between pathologists and oncologists to test for and identify TRK fusion-positive lung cancer patients.

Other Episodes

Episode

September 11, 2024 00:29:55
Episode Cover

Neuroendocrine tumours (NETs) – Shared decision-making. Part 1: Patient journey

In this first episode of a two-part podcast series focusing on neuroendocrine tumours (NETs), gastroenterologist Dr Mohid S Khan and NET patient Sally Jenkins...

Listen

Episode

December 06, 2023 00:21:48
Episode Cover

Prostate cancer: Radiopharmaceuticals. Part 2 - PSMA theranostics

Dr. Tanya Dorff (City of Hope Comprehensive Cancer Center, Los Angeles, USA) and Dr. Phillip Koo (Banner MD Anderson Cancer Center, Arizona, USA) discuss...

Listen

Episode

December 06, 2023 00:22:24
Episode Cover

Sarcoma: Updates from CTOS 2022

In this podcast, Prof. Jonathan Trent and Prof. Robin Jones discuss what’s new in the patient management in sarcoma from CTOS 2022. The Connective...

Listen