RCC: Treating advanced RCC - The role of VEGFR-TKIs alone or in combination therapy

December 06, 2023 00:20:49
RCC: Treating advanced RCC - The role of VEGFR-TKIs alone or in combination therapy
COR2ED - Oncology Medical Conversation
RCC: Treating advanced RCC - The role of VEGFR-TKIs alone or in combination therapy

Dec 06 2023 | 00:20:49

/

Show Notes

Prof. Thomas Powles, a Medical Oncologist from Barts Cancer Centre in the UK and Prof. Georg Hutterer, a Urologist from the Medical University of Graz, Austria, discuss the role of VEGFR-TKIs in the treatment of advanced renal cell carcinoma (RCC) alone or in combination with immunotherapy.

In this podcast, by COR2ED Medical Education, the two experts discuss key trials (CHECKMATE 214, KEYNOTE 426, CHECKMATE 9ER and CLEAR) which have led to recent updates to the ESMO and EAU treatment guidelines for RCC. Combination treatment with either VEGFR targeted therapy plus a PD-1 or CTLA-4 inhibitor in the first-line setting is discussed as well as VEGFR-TKI monotherapy options at the time of disease progression.

They also focus on how to manage treatment toxicity whilst trying to optimise treatment outcomes and preserving patients’ quality of life as well as the use of biomarkers and risk stratification models.

Other Episodes

Episode

May 28, 2024 00:21:47
Episode Cover

Regional differences in NET: Epidemiology, diagnosis, and referral strategies

In this first episode of a two-part podcast series, Prof. Martyn Caplin and Prof. Rachel Riechelmann discuss regional differences in NET epidemiology, and patient...

Listen

Episode

December 06, 2023 00:30:22
Episode Cover

HCC: Updates from ILCA and ESMO 2022

In this HCC CONNECT podcast HCC Experts Prof. Matthias Pinter and Prof. Jeroen Dekervel, discuss and debate the clinical implications of new HCC Phase...

Listen

Episode

December 06, 2023 00:20:43
Episode Cover

Multiple Myeloma: Choosing the best treatment regimen in newly diagnosed patients - Part 1

In this medical education podcast series, myeloma experts Dr. Joshua Richter (Assistant Professor of Medicine and Director of Myeloma at the Tisch Cancer Institute...

Listen