RCC: Treating advanced RCC - The role of VEGFR-TKIs alone or in combination therapy

December 06, 2023 00:20:49
RCC: Treating advanced RCC - The role of VEGFR-TKIs alone or in combination therapy
COR2ED - Oncology Medical Conversation
RCC: Treating advanced RCC - The role of VEGFR-TKIs alone or in combination therapy

Dec 06 2023 | 00:20:49

/

Show Notes

Prof. Thomas Powles, a Medical Oncologist from Barts Cancer Centre in the UK and Prof. Georg Hutterer, a Urologist from the Medical University of Graz, Austria, discuss the role of VEGFR-TKIs in the treatment of advanced renal cell carcinoma (RCC) alone or in combination with immunotherapy.

In this podcast, by COR2ED Medical Education, the two experts discuss key trials (CHECKMATE 214, KEYNOTE 426, CHECKMATE 9ER and CLEAR) which have led to recent updates to the ESMO and EAU treatment guidelines for RCC. Combination treatment with either VEGFR targeted therapy plus a PD-1 or CTLA-4 inhibitor in the first-line setting is discussed as well as VEGFR-TKI monotherapy options at the time of disease progression.

They also focus on how to manage treatment toxicity whilst trying to optimise treatment outcomes and preserving patients’ quality of life as well as the use of biomarkers and risk stratification models.

Other Episodes

Episode

December 06, 2023 00:38:59
Episode Cover

Prostate cancer: Highlights from ASCO GU 2022

COR2ED Medical Education: Dr Alicia Morgans, Genitourinary Medical Oncologist at the Dana-Farber Cancer Institute in the United States and Dr. Neal Shore, Uro-Oncologist and...

Listen

Episode

February 23, 2024 00:32:21
Episode Cover

Ovarian cancer: Pre-analytical phase challenges and biomarker testing

What are the common pre-analytical phase challenges in ovarian cancer, and how can we overcome them? Why is it important to identify genetic alterations?  ...

Listen

Episode

December 06, 2023 00:27:20
Episode Cover

Managing thrombosis: Part 2 - Cancer and thrombosis

In this podcast episode, Prof Dimitrios Tsakiris (Haematologist, Basel University, Switzerland) and Dr Lars Asmis (Haematologist, University of Zurich, Switzerland) discuss the association between...

Listen